November 20, 2019
"Matrix remodeling, cellular plasticity and metabolism: Insights from TGF beta signaling" by Dr. Mythreye Karthikeyan, University of Alabama at Birmingham
The mission of the Medical University of South Carolina Digestive Disease Research Center (MUSC DDRC) is to enhance research infrastructure and expand research capacity to enable outstanding, collaborative biomedical research in digestive and liver diseases.
The Center is dedicated to fostering and facilitating the interdisciplinary and collaborative research of its 55 current members and the career development of junior faculty. Currently, twenty-five full members contribute to a stable research base of $8.3M. The DDRC also seeks to attract established investigators who are not currently involved in digestive disease research to apply their expertise to this important area and help translate basic research discoveries to the clinical arena.
The Center’s central theme is focused on the continuum of organ injury, inflammation, and fibrosis - leading to disease. This continuum is highly relevant in the vast majority of digestive and liver diseases; some examples include the esophagus (esophagitis), stomach and small bowel, liver (represented in almost all forms of liver injury), pancreas (especially chronic pancreatitis), and colon (inflammatory bowel diseases).
Thus, the key goal of the DDRC is to bring together investigators studying digestive and liver diseases and provide them with core resources and collaborative opportunities to further their scientific inquiries.