Artificial Intelligence

Surgical Outcomes Research and Innovation Nucleus (SORIN) Supports Investigator-Initiated Clinical Trials

The Surgical Outcomes Research and Innovation Nucleus (SORIN) was formalized in 2019 and serves to foster the development, testing and implementation of innovative therapeutic and health services interventions aimed at improving outcomes in patients undergoing surgery at MUSC.

SORIN has a diverse and active portfolio of clinical research endeavors, including nearly 50 ongoing clinical trials across all surgical disciplines housed within the Department of Surgery.

We actively follow nearly 600 patients enrolled in our trials. We are currently testing new drug therapies, devices and cellular-based interventions designed to improve and extend the lives of South Carolinians seeking surgical care within our institution.

Embedded within SORIN and an arm of the Transplant Research and ImmunoBiology Institute (TRII) is the Transplant Clinical Research Core (TCRC).

The main function of the TCRC is to facilitate the benchtop-to-bedside concept within organ transplantation by streamlining the process of innovative therapies moving from the laboratory to clinical trials and use within usual care.

  • The TCRC currently oversees 15 clinical trials, of which nine are actively enrolling and six are in the follow-up phase.
  • Within these 15 trials, we actively follow 262 transplant recipients.
  • These clinical trials are testing novel therapies and innovations designed to improve outcomes in transplantation.