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2022 Charleston HFpEF Conference

Charleston HFpEF Conference: The Latest Knowledge on Heart Failure with Preserved Ejection Fraction

March 4-6, 2022

Francis Marion Hotel
Charleston, SC

Conference Description

Target Audience

This course is intended for cardiovascular specialists, heart failure specialists, practicing cardiologists, cardiovascular advanced practice providers (NP or PA), internists, family physicians, pharmacist, cardiovascular nurses, critical care nurses, and industry representatives.

Knowledge Gaps

There are now more patients who have Heart Failure with preserved Ejection Fraction (HFpEF) than those with reduced Ejection Fraction (HFrEF). Making the diagnosis of HFpEF is more challenging than HFrEF as many commonly used screening tools such as physical examination, echocardiography and measurement of natriuretic peptide levels are less sensitive and specific in this population. Most importantly, no therapies have yet been shown to improve major cardiovascular outcome (i.e. reductions in hospitalization rates or lower mortality). Several ongoing studies are evaluating novel treatments for this disorder.

Conference Schedule and Faculty 

The conference schedule and faculty listing will be available soon.


  • Discuss the pathophysiology of pulmonary vascular disease in HFpEF
  • Describe the prognostic implications of pulmonary vascular disease in HFpEF
  • Discuss potential treatments for pulmonary vascular disease in HFpEF
  • Distinguish features of HFpEF that suggest underlying cardiac amyloidosis
  • Discuss current and emerging therapies addressing the pathophysiology of amyloid.
  • Define hemodynamic causes symptoms/signs in acute decompensated heart failure (ADHF)
  • Discuss time course of changes in hemodynamics leading to ADHF
  • Describe how to use remote monitoring to detect and predict ADHF
  • Demonstrate how to use effective remote monitoring in CHF management to change outcomes, prevent ADHF
  • Appreciate the pathophysiological abnormalities in HFpEF that would likely improve with classical inotropic agents
  • Identify patients with HFpEF who are potential candidates for therapy with inotropic agents
  • Prescribe inotropic agents to overcome diuretic resistance or refractory volume overload in patients with advanced HFpEF
  • Discuss the increasing recognition of heart failure with preserved ejection fraction in the peri-partum period
  • Recognize risk factors for pregnancy associated HFpEF
  • Identify the long-term cardiovascular risks for women with pregnancy associated HFpEF
  • Summarize the data available to date on SGLT2 inhibitors in populations with heart failure and preserved ejection fraction
  • Identify patients who might be most likely to benefit from SGLT2 inhibitors
  • Appreciate the contribution of the lymphatic system to the pathology of heart failure
  • Apply the dynamics of lymph production and drainage to the clinical care of heart failure patients 
  • Review the pathophysiology and epidemiology of pulmonary vascular disease associated with lung diseases
  • Discuss the contribution of pulmonary vascular disease to the morbidity associated with HFpEF
  • Review the evaluation of pulmonary disease in the HFpEF patient
  • Describe the management of pulmonary diseases in the HFpEF patient
  • Recognize clinical significance of NAFLD; Identify shared risk factors between NAFLD and HFpEF
  • Identify individuals who may need evaluation for NAFLD and / or HFpEF
  • Identify the differential impact of cardiovascular risk factors on risk for HFPEF among various demographic subgroups
  • Identify the impact of social determinants of health on traditional cardiovascular risk factors
  • Develop a patient-centered approach to cardiovascular risk factor reduction that takes social determinants of health into account  
  • Identify arterial stiffness as an important contributor to HFpEF pathophysiology
  • Discuss current therapeutic approaches to arterial stiffness in HFpEF
  • Describe sex differences in arterial stiffness as it relates to HFpEF
  • Discuss the rationale for use of exercise training and dietary weight loss in the treatment of HFpEF
  • Become proficient in data supporting diet and exercise in HFpEF for improving key patient-oriented outcomes
  • Enhance insight into mechanisms of improvements in outcomes with diet and exercise in HFPEF
  • Define the clinical difficulty presented by diuretic resistance in HFpEF
  • Delineate proposed pathophysiologic pathways causal in diuretic resistance
  • Review the literature and evidence for proposed therapies to combat diuretic resistance in HFpEF
  • Recall the epidemiology of body composition abnormalities among patients with HFpEF
  • Describe the relationships between sarcopenia, functional capacity and survival for patients with HFpEF
  • Articulate the benefits of exercise training and cardiac rehabilitation for patients with HFpEF

Online Syllabus

The syllabus will be provided online during the conference, and for up to 30 days after the conference ends. Information will be emailed to you a few days prior to the conference so that you may download a copy.

Credit Designation

Physician Credit Statement

The Medical University of South Carolina designates this live activity for a maximum of 12.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Other Credit Statements

Nurses: Most states accept CMEs that apply to a specific nursing specialty as nursing continuing education. Please check with your respective State Board of Nursing to ascertain the equivalent number of contact hours offered for 12.0 AMA PRA Category 1 Credit(s)™.

PAs: AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit(s)™ and Prescribed credit from AAFP from organizations accredited by ACCME or a recognized state medical society. The MUSC Office of CME provides certificates to PAs with a statement, approved by AAPA, that PAs may receive a maximum of 12.0 AAPA Category 1 Credits for this conference.

ABIM MOC logoSuccessful completion of this CME activity which includes participation in the evaluation component, enables the participant to earn up to 12.0 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.


In accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education anyone involved in planning or presenting this educational activity will be required to disclose any financial relationships with any ineligible companies. An ineligible company is any entity whose primary business is producing, marketing, selling, reselling, or distributing healthcare products used by or on patients. Any financial relationships with these ineligible companies have been mitigated by the MUSC Office of CME. Speakers who incorporate information about off-label or investigational use of drugs or devices will be asked to disclose that information at the beginning of their presentation.


The Medical University of South Carolina College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Americans with Disabilities Act

It is the policy of the Medical University of South Carolina not to discriminate against any person on the basis of disabilities. If you feel you need services or the auxiliary aids mentioned in this act in order to fully participate in this continuing education activity, please call the Office of Continuing Medical Education at (843) 876-1925, or attach a note to your registration.

Registration Fees 

The registration fees for in-person attendance and virtual attendance are the same. 

Early Bird                               Regular
(on/before 12/31/2021)           (after 1/1/2022)

Practicing Physicians $350                                        $400
Other Healthcare Specialist $250                                        $300
MUSC Employee* $250                                        $250

*MUSC Division of Cardiology faculty and staff should call the Office of CME at 843-876-1925 to register.   

The fee for in-person attendance includes tuition, breaks, online syllabus, and certificates of attendance. The fee for live streaming the meeting includes tuition, online syllabus, and certificates of attendance.

Pre-registrations will be accepted until February 25, 2022 or until the conference capacity is reached. After this date, you must contact the MUSC Office of CME ( or 843-876-1925) to see if space is still available.

Registration Methods

(Please use ONE of these methods to register. Do not mail if previously faxed or telephoned).

Mail registration form with check made out to “Medical University of South Carolina” or credit card information to:

Elizabeth Gossen MUSC Office of CME 96 Jonathan Lucas Street HE 221A, MSC 754 Charleston, SC, 29425

Telephone: (843) 876-1925 – Registration by credit card only

Fax: (843) 876-1931 – Registration by credit card only


Click here for Online Registration Conference Portal

Conference Cancellation

A refund will be made upon written request prior to February 4 , 2022; however, $100 will be retained for administrative costs. No refunds will be made after February 4, 2022. We reserve the right to cancel the program if necessary. Full registration fees will be refunded for cancelled programs.  By registering for this conference, you agree to this cancellation policy.

Hotel Information

The Francis Marion Hotel
387 King Street
Charleston, SC 29403
(843) 722-0600

The Francis Marion Hotel, historic Charleston’s landmark full service hotel, is in the heart of Charleston’s historic district. Located at the newly restored Marion Square, the Francis Marion Hotel is only a few blocks from the Charleston Visitor Center, South Carolina Aquarium, restaurants, boutiques, galleries, museums, antique shops and night life. The hotel offers valet parking, spa, concierge, retail shops and the Swamp Fox Restaurant & Bar. Special group rates start at $289.00, plus tax, per night. A limited number of guest rooms have been reserved and are being offered on a first come, first serve basis. The room block will be held until February 2, 2022 however the room block may be filled prior to this date. In such a case, neither the group rate nor guest room availability can be guaranteed. Therefore, we recommend you make your reservation as soon as possible. Reservations can be made by calling the hotel directly at 843-722-0600 or 877-756-2121 and identifying yourself as being a participant in this meeting, or by following the online directions below. Link for online reservations:

Click here for the Hotel Online Booking Link

Parking: Valet parking at the hotel is available at $25.00 plus tax, per day and can be added to your guest folio. In addition, self-parking is available at $20.00 per day (cash). Rates are subject to change with notice.

Pandemic Uncertainty

The lack of certainty about the future trajectory of the pandemic makes it difficult to make an informed decision about almost everything.  With this in mind, we have listed some key points to consider as you decide between the in-person registration and the virtual registration:

  • Wearing a mask will be required in the conference room whether you are vaccinated or not.
  • If you make a hotel reservation at the Francis Marion Hotel, it can be cancelled up to one week prior to your arrival day. The phone number for the Francis Marion is 843.722.0600
  • We will not be offering COVID Testing onsite at the conference
  • If you are traveling internationally, please refer to the CDC Requirements for International Travelers prior to making your arrangements
  • For everyone flying to Charleston, we suggest purchasing travel insurance in the event your trip is cancelled.