22nd ISRHML Agenda

Monday, December 9, 2024

8:30am Optional Workshop 1 (Stay tuned for more information)

1:00pm Optional Workshop 2 (Stay tuned for more information)

5:00 Welcome Reception

7:00 Reception Concludes

Tuesday, December 10, 2024

8:00am Welcome Address

8:30 Macy-Gyorgy Award Announcement and Recipient Lecture

10:00 Break - Discussions and Networking

10:30 Session 1: New Discoveries in Immunologic Functions of Breast Milk
Human milk antibodies in infectious diseases – do they really matter? Kirsi Järvinen-Seppo, MD, PhD Human milk-derived immunoglobulin A reactivity against microbiota, Timothy Hand (Virtual) Maternal protection from enteric pathogens, Laxmi Yeruva, PhD Oral presentations based on abstracts

12:00pm Lunch provided

1:00 Session 2: The Impact of Maternal Condition on Lactation, Laurie Nommsen-Rivers, Donna Geddes, Rebekah Hoban
Exploration of the metabolic demands of lactation and its potential implications for maternal health, both short-term and long-term; Breastfeeding's impact on maternal weight loss, postpartum metabolic changes, and long-term health outcomes; Impact of maternal obesity and type 2 diabetes on initial and sustained lactation; Maternal higher BMI and its effects on lactation initiation and sustained lactation; Maternal diabetes (gestational, type 1 and type 2) - differences in milk production, composition, and immune markers; Insights into impaired lactation and potential interventions - Four 15-min oral presentations from abstracts; Oral presentations based on abstracts

3:00 Break - Discussions and Networking

3:30 Session 3: Findings from the International Milk Composition Consortium (IMiC): A Multidisciplinary Approach to Studying Human Milk as a Biological
System and Understanding its Relationship with Infant Growth
Part A - Overview + Integrated Multi-Omic Results IMiC: A multi-omics view of human milk composition across diverse geographies and environments Multi-omics methods in IMiC + Human milk composition in relation to maternal factors Human milk composition in relation to infant anthropometry Human milk composition following balanced energy protein or nicotinamide supplementation in three RCTs Part B - Single Omic Results Human Milk Metabolomics in IMiC Human Milk Microbiota in IMiC Colostrum in IMiC Part C - Learnings and applications Flash Talks from Poster Presenters: nutrients, proteomics, HMOs, targeted proteins LMIC Learnings from IMiC Panel Discussion: research, practice, policy and products

5:45 Poster Symposium 1

Wednesday, December 11, 2024

8:00am Session 4: Human Milk as a Biological System, Dr. Ellen Demerath, Dr. Meghan Azad, Dr. Bridgette Young
Intro to BEGIN; Updates from NIH

10:00 Break - Discussions and Networking

10:30 Session 5: Public Health Interventions and Economics of Breastfeeding Around the World, Dr. Tricia Johnson, Rafael Pérez-Escamilla
Policy initiatives to promote breastfeeding, including maternity leave policies and workplace accommodations; Public health and healthcare system interventions to increase breastfeeding; Interventions to improve equity and inclusion in breastfeeding interventions; Economic evaluations of interventions to increase breastfeeding exclusivity and duration; Oral presentations based on abstracts

12:00pm Lunch/TIG Professional Development Panel

1:30 Session 6: Genomics, Epigenetics and Transcriptomics of Human Milk, Brittany Goods
Host genetic and epigenetic factors related to regulation of human milk composition; Transcriptomics of the mammary gland; Epigenetic studies examining how breastfeeding can influence gene expression and long-term health outcomes in offspring; The interplay between genetics, breastfeeding, and epigenetic modifications; Oral presentations based on abstracts

3:00 Break - Discussions and Networking

3:30 Session 7: Breastfeeding and Chronic Disease Prevention, Berthold Koletzko
What are the potential protective long-term effects of breastfeeding against chronic diseases such as obesity, diabetes, and cardiovascular diseases; Mechanisms through which breastfeeding may confer long-term health benefits; Later in Life: Life-expectancy of those who breastfeed, partially breastfeed vs. those who do not around the globe: is there a threshold in duration of Breastfeeding; 
Oral presentations based on abstracts

5:00 Annual General Membership Meeting

6:00 Poster Session 2

Thursday, December 12, 2024

8:00am Session 8: The Mothers, Infants and Lactation Quality (MILQ) Study
Part A - Overview + Rationale: Reference Values for milk nutrients Why lactation research needs Reference Values Reference Values for milk Vitamins Reference Values for milk minerals Reference Values for milk vitamins Part B - Measurement Challenges Analytical Methods Practical Challenges Statistical Challenges Part C - Human Milk Composition: Determinants and Broader Insights Milk Volume and Micronutrient Status Maternal Diet and Micronutrient Status HMOs Microbiome Genome Part D: Panel Discussion: Research, practice, policy and products

10:00 Break - Discussions and Networking

10:30 Session 9: Maternal Impact on Short- and Long-term Infant Health
Studies on how human milk composition is associated with the development of the infant microbiomes (oral and gastrointestinal);
Differences between term and preterm infants;
Role of human milk oligosaccharides (HMOs) in shaping gut microbial composition and function;
Human milk proteins and peptides - potential impacts on infant health;
Oral presentations based on abstracts

12:00pm Lunch/Meet the Experts

1:00 Afternoon free to explore Charleston

6:00 ISRHML Gala Event (Dinner, Awards, Networking)

Friday, December 13, 2024

8:30am Session 10: Impact of Climate and Environment on Lactating Parent/Human Milk/Infant Triad
Impacts of climate on milk production and composition in dairy animals;
Positive effects of breastfeeding on climate;
Potential impact of climate and environment on lactation and milk composition in humans;
Oral presentations based on abstracts

10:00 Break - Discussions and Networking

10:30 Session 11: Innovations in Breastfeeding Support
Advances in breastfeeding technologies, such as wearable breast pumps and lactation apps;
Benefits and limitations of milk analyses in prescribing fortification for the preterm and high-risk infant with growth and developmental issues;
Telehealth and virtual lactation support services;
Oral presentations based on abstracts

 11:30 Session 12: Hot Topics & Breaking Research
Presentations chosen from abstracts reviewed by the Scientific Planning Committee

12:15pm Wrap-up with Box Lunch

12:45 Adjourn