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Projects of COBRE Digestive & Liver Disease

Transforming Digestive & Liver Research Together

At the Center of Biomedical Research Excellence (COBRE) in Digestive and Liver Disease, our projects foster innovation and collaboration across scientific disciplines to advance understanding and treatment of digestive and liver conditions. From pilot programs that seed bold ideas to research that shapes national impact, the center empowers investigators to pursue discovery with purpose and excellence. These initiatives engage faculty, postdoctoral fellows, and trainees in creating pathways to groundbreaking scientific and clinical advances.

Advancing Innovation Through Shared Knowledge

The Enrichment Series brings leading voices in science and medicine to MUSC, inspiring collaboration and sparking discovery. From the Digestive Disease Seminar Series to the annual Scientific Retreat, these experiences connect investigators, foster mentorship, and elevate innovation in digestive and liver research.

Learn About the Series

Empowering the Next Generation of Investigators

The Pilot Project Program accelerates bold ideas by empowering MUSC scientists to explore novel approaches in digestive and liver disease research. Through competitive funding, mentorship, and collaboration, the program transforms early-stage concepts into promising foundations for major grants and future breakthroughs.

Learn About the Program

Our pilot projects highlight innovative studies by MUSC researchers exploring digestive and liver disease mechanisms. Discover current projects that demonstrate early-stage ideas evolving into high-impact scientific contributions.

COBRE Research Projects

Our research projects are faculty-led studies advancing molecular, cellular, and translational understanding of digestive and liver diseases. Investigations reflect MUSC’s scientific leadership and collaborative innovation.

Current Projects

  • Glutamine Metabolism and Macrophage Function in Hepatocellular Carcinoma
  • Enteric Neuron–Intestinal Stem Cell Signaling in Host Defense
  • p53 and Ferroptosis in Cancer Disparities
  • Redox Regulation of β-Cell Function in Diabetes

Watch this space for project details coming soon.

COBRE Alumni Projects

Alumni Projects feature former center investigators whose research continues to shape the field of digestive and liver disease. Explore how their work extends MUSC’s legacy of discovery, collaboration, and scientific excellence beyond our campus.