About the Division of Gastroenterology & Hepatology

Brenda Hoffman, M.D. is a professor of medicine in the Division of Gastroenterology and Hepatology at the Medical University of South Carolina. She also serves as Chief of Digestive Health for the MUSC Health Integrated Center of Clinical Excellence (ICCE). 

Dr. Hoffman received her M.D. degree from the University of Kentucky College of Medicine in 1983 and completed her gastroenterology fellowship at the Medical University of South Carolina in 1989. She is board certified in internal medicine and gastroenterology. Dr. Hoffman is a member of several organizations, including the American Gastroenterological Association, American Society of Gastrointestinal Endoscopy, American College of Gastroenterology, American College of Physicians, American Endosonography Club, Charleston Medical Society, Southern Medical Association, and the South Carolina Gastroenterology Association.

Dr. Hoffman has received numerous honors, including the Faculty Excellence Award, Top 20 Female Physicians -- Southern Woman to Woman, Who's Who/Physicians of the Southeast, American Society of Gastrointestinal Endoscopy Audio/Visual Award, America's Top Doctors, and Best Doctors.

Dr. Hoffman's clinical interests are endoscopic ultrasound, endoscopic submucosal dissection, endoscopic mucosal resection, ablative therapy for Barrett's esophagus, capsule endoscopy, laser therapy and therapeutic endoscopy. Her clinical research interests are in endoscopic intervention and prevention and control.

Brenda Hoffman, M.D. is a professor of medicine in the Division of Gastroenterology and Hepatology at the Medical University of South Carolina. She also serves as Chief of Digestive Health for the MUSC Health Integrated Center of Clinical Excellence (ICCE). 

Dr. Hoffman received her M.D. degree from the University of Kentucky College of Medicine in 1983 and completed her gastroenterology fellowship at the Medical University of South Carolina in 1989. She is board certified in internal medicine and gastroenterology. Dr. Hoffman is a member of several organizations, including the American Gastroenterological Association, American Society of Gastrointestinal Endoscopy, American College of Gastroenterology, American College of Physicians, American Endosonography Club, Charleston Medical Society, Southern Medical Association, and the South Carolina Gastroenterology Association.

Dr. Hoffman has received numerous honors, including the Faculty Excellence Award, Top 20 Female Physicians -- Southern Woman to Woman, Who's Who/Physicians of the Southeast, American Society of Gastrointestinal Endoscopy Audio/Visual Award, America's Top Doctors, and Best Doctors.

Dr. Hoffman's clinical interests are endoscopic ultrasound, endoscopic submucosal dissection, endoscopic mucosal resection, ablative therapy for Barrett's esophagus, capsule endoscopy, laser therapy and therapeutic endoscopy. Her clinical research interests are in endoscopic intervention and prevention and control.

Dr. Alexander J. Podboy is a board-certified gastroenterologist and interventional endoscopist at MUSC Health, specializing in advanced, minimally invasive treatments for complex gastrointestinal conditions. He completed his residency at Mayo Clinic in Rochester, Minnesota, followed by fellowships in gastroenterology at Stanford University and advanced endoscopy at Cedars-Sinai Medical Center in Los Angeles. His training established expertise in therapeutic endoscopy, foregut motility disorders, and endobariatric procedures.

In addition to his clinical work, Dr. Podboy conducts research focused on the immune mechanisms underlying achalasia and gastroparesis. He utilizes innovative approaches such as single-cell sequencing and machine-learning models to improve diagnosis and treatment, with the goal of advancing care for patients with complex gastrointestinal diseases.