Research Overview
Dr. Squeglia’s research focuses on understanding the effects of alcohol and cannabis use on adolescent brain development, using structural and functional neuroimaging and neuropsychological testing, as well as creating effective treatment options for substance-using youth. She co-leads MUSC’s site for the nationwide Adolescent Brain Cognitive Development Study (ABCD). She is funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA).
You can learn more about research in the Squeglia Lab by exploring our studies below.
Ongoing Studies
Adolescent Brain Cognitive Development (ABCD) Study
The Adolescent Brain Cognitive Development (ABCD) Study is the largest long-term study of brain development and child health in the United States. The ABCD Research Consortium consists of 21 research sites across the country, which will follow 11,874 children from ages 9 to 20. Researchers will observe their biological and behavioral development through adolescence into young adulthood.
Status: Closed. The ABCD Study is no longer enrolling new participants.
Visit the ABCD Study Page for more information.
View project details on NIH Reporter.
NAC for Youth Alcohol Use
This project is an important step in understanding the effects of N-acetylcysteine (NAC) as a possible treatment for teen alcohol use. Successful treatment could prevent teen drinking and lower the chance of long-lasting problems, helping teens and their communities.
Status: Open. The NAC for Youth Alcohol Use study is accepting new participants.
Visit the NAC for Youth Alcohol Use Study Page
View project details on NIH Reporter.
Understanding Teen Alcohol Use
Many people first try alcohol during adolescence, which is an important time for brain growth. The goal of this study is to understand how alcohol use affects teens' brains and how N-acetylcysteine (NAC) might help teens stop drinking.
Status: Open. The Understanding Teen Alcohol Use Study is accepting new participants.
Visit the Understanding Teen Alcohol Use Study Page
View project details on NIH Reporter.