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Medical Scientist Training Program

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Program Overview

The Medical Scientist Training Program (MSTP) at the Medical University of South Carolina prepares future physician scientists through an integrated M.D. and Ph.D. curriculum that unites medical education with rigorous biomedical research. Students receive comprehensive clinical training while pursuing in depth, hypothesis driven research under expert mentorship. The program emphasizes discovery, translation, and professionalism, equipping graduates to advance human health and lead impactful careers in academic medicine and research.

Application Timeline

Jul 1 – Dec 1

Learning Experience

Step into a fully integrated pathway that unites medical training and scientific discovery, equipping you to become a physician scientist who leads at the intersection of research and patient care.

Inside the Program

We are committed to maintaining the highest standards for both the Ph.D. and M.D. degrees. Our program provides a collegial and nurturing environment in which each student’s intellectual and personal potential is nurtured, encouraged and challenged. This ensures that our trainees achieve their full potential. Upon completion of their training, our students go on to the highest quality internships, residency training programs and post-doctoral research fellowships, followed by outstanding career positions.

The MSTP offers maximum flexibility and guidance for the student to select a mentor and training experience. There are also several mechanisms available that allow the trainee to get significant exposure to clinical and translational research during the graduate years in addition to time in medical school. They include but are not limited to the Translational Sciences Clinic (during graduate years), Translational Medicine Seminar Series, a Month in the Research Nexus (during senior year) and the CARES Clinic, an evening clinic serving the medically indigent. Our students publish their research in top-tier journals and receive numerous honors and awards for their research.

Curriculum

Year 1, Fall

Course ID Course Title Credits
MDCOR711 Clinical Skills 1 3
MDCOR720 Foundations of Health 8
MDCOR722 Foundations of Disease 9
MDCOR725 Cardiovascular Systems 9
Semester Total 29

Year 1, Spring

Course ID Course Title Credits
MDCOR712 Clinical Skills 2 3
MDCOR727 Respiratory/Renal Systems 7
MDCOR728 Gastrointestinal 9
MDCOR731 Reproductive/Endocrine Systems 8
IP711 IP Foundations & TeamSTEPPS 1
Semester Total 28

Year 1, Summer

Course ID Course Title Credits
MDCOR713 Clinical Skills 3 3
MDCOR733 Women & Pediatric Health 5
MDCOR735 Ethics & Biostatistics 3.5
MDCOR736
Autoimmunity & Hematology 5
Semester Total 16.5

Year 2, Fall

Course ID Course Title Credits
MDCOR714 Clinical Skills 4 3
MDCOR739 Sensory & Motor Systems 13
MDCOR741 Special Senses & Cognition 8
MDCOR742 Behavioral & Geriatric Health 4.5
IP### IP concentration course of choice 1
Semester Total 29.5

Year 2, Spring

Course ID Course Title Credits
MDCOR750
USMLE Step 1 Board Review 2
CGS820 MSTP Seminar 0.5
RSCH Research 13
Semester Total 15.5

Year 2, Summer

Course ID Course Title Credits
RSCH Research 15
Semester Total 15

Year 3, Fall

Course ID Course Title Credits
CGS765 Proteins: Dynamic Structures & Functions 1
CGS766 Genes: Inheritance/Expression 2
CGS767 Cells: Organization/Communication 2
CGS768 Techniques & Experimental Design 2
RSCH Research 8
Semester Total 15

Year 3, Spring

Course ID Course Title Credits
CGS770 Principles Practices & Prof 2
CGS772 Learning from the Literature 2
RSCH Research 11
Semester Total 15

Year 3, Summer

Course ID Course Title Credits
CGS764 Science Writing as Persuasion 1
RSCH Research 14
Semester Total  15

Year 4, Fall

Course ID Course Title Credits
RSCH Research 10
DEPT Any additional department specific requirements  
Semester Total 15+

Year 4, Spring

Course ID Course Title Credits
RSCH Research 15
DEPT Any additional department specific requirements  
Semester Total 15+

Year 4, Summer

Course ID Course Title Credits
RSCH Research 15
DEPT Any additional department specific requirements  
Semester Total 15+

Year 5, Fall

Course ID Course Title Credits
RSCH Research 15
DEPT Any additional department specific requirements  
Semester Total 15+

Year 5, Spring

Course ID Course Title Credits
RSCH Research 15
DEPT Any additional department specific requirements  
Semester Total 15+

Year 5, Summer

Course ID Course Title Credits
RSCH Research 15
DEPT Any additional department specific requirements  
Semester Total 15+

Year 6, Fall

Course ID Course Title Credits
RSCH Research 15
DEPT Any additional department specific requirements  
Semester Total 15+

Year 6, Spring

Course ID Course Title Credits
RSCH Research 15
DEPT Any additional department specific requirements  
Semester Total 15+

Year 6, Summer

Course ID Course Title Credits
MDCOR866 Transition to Clinical Medicine 1
CLRK Clerkship* (6-week) 6
CLRK Clerkship* (6-week) 6
CLRK Clerkship* (6-week) 6
CLRK Clerkship* (6-week) 6
Semester Total 25

Year 7, Fall

Course ID Course Title Credits
MDCOR835 Topics in Clinical Medicine 1
MDCOR853 Ethics in Clinical Care 3A 1
MDCOR872 Geriatric Medicine 3A 0.5
CLRK Clerkship* (8-week) 10
SLCT Selective (2-week) 2.5
SLCT Selective (2-week) 2.5
Semester Total 17.5

Year 7, Spring

Course ID Course Title Credits
MDCOR854 Ethics in Clinical Care 3B 1
MDCOR873 Geriatric Medicine 3B 0.5
CLRK Clerkship* (6-week) 8
CLRK Clerkship* (6-week) 8
CLRK Clerkship* (6-week) 8
Semester Total 25.5

Year 7, Summer

Course ID Course Title Credits
MDCOR865 Clinical Competency Exam 3 1
ELEC Critical Care Elective (4-week) 5
XTRN Externship (4-week) 5
Semester Total 11

Year 8, Fall

Course ID Course Title Credits
MDCOR859
Ethics in Clinical Care 4A 1
EMED822 Essentials of Emergency Medicine 2.5
ELEC Electives (12-week) 15
Semester Total 18.5

Year 8, Spring

Course ID Course Title Credits
MDCOR626 Internship 101 2.5
MDCOR862 Ethics in Clinical Care 4B 1
MDCOR874 Geriatric Medicine 4 1
ELEC Electives (12-week) 15
Semester Total 19.5
Curriculum Total 415.5+

Clinical Experience

MSTP students complete the full M.D. curriculum alongside their medical classmates, gaining broad and immersive clinical training across foundational and advanced experiences. Clinical exposure begins early and continues throughout the program to ensure strong continuity between patient care and research training. Students engage with diverse patient populations and clinical environments that help shape meaningful research questions grounded in real-world health challenges. This sustained clinical engagement reinforces professional identity, sharpens clinical reasoning, and strengthens the ability to translate discovery into improved care.

Research Experience

Research training is the centerpiece of the MSTP experience. Students explore research areas early through rotations before committing to focused doctoral training guided by accomplished faculty mentors. The program supports deep laboratory immersion, rigorous graduate coursework, and exposure to translational research environments that connect science to human health. Through sustained investigation, scholarly dissemination, and close mentorship, trainees develop the skills needed for independent research careers and future leadership within the biomedical research enterprise supported by the National Institutes of Health.

Your path to admission

Discover key information about application steps and required documentation to help you move forward with confidence.

Eligibility Requirements

GPA and MCAT scores are a large factor in obtaining an interview, at which point we are looking for the other traits essential to becoming great physicians.

All applicants must:

  • Possess a bachelor's degree prior to matriculation in to the program
  • Have obtained a minimum cumulative GPA of 3.5 on a 4.0 scale
  • Have obtained a minimum MCAT score of 504 taken within three years from the date of matriculation (July 1)
  • Supply record of advanced courses in the physical and/or biological sciences
  • Demonstrate evidence of serious and enthusiastic commitment to the program
  • Demonstrate evidence of a commitment to research through clinical shadowing experience and/or volunteer work
  • Not be currently or have been previously enrolled in an M.D. or Ph.D. program outside of MUSC

We are particularly interested in why you want to come to MUSC for the MSTP and what research you would like to pursue in graduate school. The committee takes a holistic approach in the evaluation of the applications.

Application Process

Application Deadlines

Start Term Application Type Available Deadline
Fall 2026 Regular Jul 1, 2025 Dec 1, 2025

Fees

Fee Type Fee
Application Fee (per application) $95
Matriculation Fee (upon applicant acceptance) $485

Start Your Application

Application Requirements

  1. AMCAS ApplicationThe following materials must be submitted through the AMCAS application. Applicants do not need to send any of the following information directly to MUSC.
    • Letters of recommendation: All applicants should submit three to five references from individuals who know the applicant well enough to comment on their education and research potential. These letters should come from prior or current research mentors, instructors, physicians, or employers. We will also accept a committee packet with three separate letters from their college pre-med advisory committee. Non-traditional students who have been away from college for a number of years can substitute an employer for one of the faculty letters.
  2. Supplemental Application: All applicants must submit the MUSC Supplemental Application.

Applicants must select the M.D./Ph.D. program type on their application. This application will permit the applicant to submit essays describing their interest in the combined M.D./Ph.D. program. Applicants should instruct AMCAS to forward their AMCAS application to MUSC.

Funding your path forward

Explore tuition and fees along with financial aid options to support your educational journey.

Tuition & Fees

Year 1

Tuition/Fee Type Fall Spring Summer Annual
In-state Tuition $7,475 $7,475 $7,475 -
Out-of-state Tuition $9,948 $9,948 $9,948 -
Basic Life Support Training Fee - - - $65
Examination & Technology Support Fee - - - $1,157
Gross Anatomy Lab Fee - - - $950
Student Disability Insurance - - - $79

Year 2

Tuition/Fee Type Fall Spring Summer Annual
In-state Tuition $7,475 $7,475 $7,475 -
Out-of-state Tuition $9,948 $9,948 $9,948 -
Examination & Technology Support Fee - - - $695
Rotation Credentialing Fee - - - $85
Student Disability Insurance - - - $79

Year 3-6

Tuition/Fee Type Fall Spring Summer Annual
In-state Tuition $7,475 $7,475 $7,475 -
Out-of-state Tuition $9,948 $9,948 $9,948 -

Year 7

Tuition/Fee Type Fall Spring Summer Annual
In-state Tuition $7,475 $7,475 $7,475 -
Out-of-state Tuition $9,948 $9,948 $9,948 -
Examination & Technology Support Fee - - - $488
Student Disability Insurance - - - $79

Year 8

Tuition/Fee Type Fall Spring Summer Annual
In-state Tuition $7,475 $7,475 $7,475 -
Out-of-state Tuition $9,948 $9,948 $9,948 -
Composite Fee - - - $34
Examination & Technology Support Fee - - - $118
Student Disability Insurance - - - $79

Cost of Attendance

Item Year 1 Year 2 Year 3 Year 4 Year 5-8 Est. Total*
Direct Costs
Tuition - In-state/
Out-of-state
$22,425/
$29,843
$22,425/
$29,843
$22,425/
$29,843
$22,425/
$29,843
$22,425/
$29,843
$179,400/
$238,744
 Health Insurance $3,780 $3,780 $3,780 $3,780 $3,780 $30,240 
Fees $2,551 $1,159 $867 $531 $300 $6,308 
Direct Costs Subtotal $28,576/
$36,174
$27,364/
$34,782
$27,072/
$34,490
$27,267/
$34,685
$26,505/
$33,923
$215,948/
$275,292
Indirect Costs
Housing/Food $27,144 $27,144 $27,144 $27,144 $27,144 $217,152
Personal $2,880 $2,880 $2,880 $2,880 $2,880 $23,040
Transportation $3,240 $3,240 $3,240 $3,240 $3,240 $25,920
Books/Required Expenses $3,860 $3,860 $3,860 $3,860 $3,860 $30,880
Indirect Costs Subtotal $37,124/
$37,124
$35,914/
$35,914
$35,414/
$35,414
$36,724/
$36,724
$34,774/
$34,774
$296,992/
$296,992
 
Total - In-state/Out-of-state $65,880/
$73,298
$63,278/
$70,696
$62,486/
$69,904
$63,991/
$71,409
$61,279/
$68,697
$512,940/
$572,284
 

Disclaimer: The Estimated Total listed above reflects an approximation of educational costs for planning purposes only. Actual expenses may vary based on individual circumstances, program requirements and annual changes in tuition, fees and other costs. The Medical University of South Carolina reserves the right to adjust tuition, fees and other charges at any time without prior notice.

Scholarships

MUSC offers scholarships for which you may be eligible. Some are awarded based on academic achievement; others are awarded based on community service, for example. However, the majority of scholarships awarded at MUSC are based on financial need. This means that these scholarships are only awarded to students who need some financial assistance to cover the cost of tuition and fees. If you would like to be considered for a financial need-based scholarship, you must have an up-to-date Free Application for Federal Student Aid (FAFSA) on file. Make sure you list the Medical University of South Carolina on your FAFSA form, along with MUSC's code: 003438. We encourage you to submit your FAFSA as early as possible. It is recommended to submit your FAFSA in January if you plan to enroll in the fall.

View scholarship opportunities

Career Outlook

Earning an M.D./Ph.D. opens the door to impactful careers at the intersection of medicine and research. Graduates are equipped with the expertise to succeed in the following roles:

  • Physician-Scientist: Combines patient care with research, leading studies that drive medical innovation. Physician-scientists often hold dual roles in academic medical centers, government research institutions, or industry.
  • Academic Researcher: Conducts cutting-edge biomedical research, secures grant funding, and mentors the next generation of physician-scientists in universities and research hospitals.
  • Clinical Laboratory Scientist: Oversees laboratory testing and diagnostics, ensuring accuracy in research and patient care. Clinical laboratory scientists work in hospitals, academic research centers, and biotechnology firms.

Graduates may find employment in academic medical centers, pharmaceutical and biotechnology companies, medical device firms, government agencies such as the NIH and FDA, and research institutions worldwide. The specialized skills acquired through this program also provide a strong foundation for those pursuing leadership roles in translational medicine, clinical trials, and healthcare innovation.

Program Faculty

Nancy Klauber-DeMore, M.D.

Director, Medical Scientist Training Program - College of Medicine
Co-leader, Developmental Cancer Therapeutics Research Program - Hollings Cancer Center
BMW Endowed Chair in Cancer Research
Professor, College of Medicine - Surgery

Donald R. Menick, Ph.D.

Professor
Medicine - Division of Cardiology

Frequently Asked Questions

The MUSC MSTP offers an integrated M.D. and Ph.D. curriculum with strong mentorship, flexibility in research training, and sustained clinical engagement throughout the program. Students benefit from dedicated translational experiences, close faculty access, and a collaborative academic medical center environment that supports physician-scientist development.

Clinical exposure begins early and continues during the research years to maintain continuity between patient care and discovery. Structured opportunities such as translational clinics, service learning experiences, and research immersion ensure that clinical insight informs scientific inquiry and translational impact.

Living in Charleston

Charleston offers a unique blend of coastal beauty and modern convenience. With top-rated dining, scenic waterfronts and endless outdoor activities, the city offers an unmatched quality of life for residents, striking a balance between work and leisure.

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Guided by purpose & principles

Join a community grounded in compassion, collaboration, respect, integrity and innovation, committed to empowering future leaders in medical science.

Objectives

The MSTP program aims to prepare graduates to:

  • Integrate rigorous biomedical research training with comprehensive medical education to advance scientific discovery and improve human health
  • Design, conduct, and lead independent, hypothesis-driven research that addresses fundamental biological mechanisms and clinically relevant problems
  • Translate scientific discoveries into clinical and population-level applications that improve diagnostics, therapeutics, and patient outcomes
  • Assume leadership roles in academic medicine and research enterprises through collaboration, mentorship, and scholarly engagement
  • Practice medicine and conduct research with the highest standards of professionalism, ethics, and integrity, recognizing the societal responsibility of physician-scientists

Competencies

Upon completion of the MSTP program, graduates should be able to:

  • Formulate significant research questions and hypotheses grounded in scientific literature and clinical observation
  • Design and implement rigorous experimental and analytical approaches appropriate to biomedical, translational, or clinical research
  • Analyze, interpret, and synthesize complex scientific and clinical data using appropriate quantitative and qualitative methods
  • Disseminate research findings effectively through peer-reviewed publications, scientific presentations, and interdisciplinary collaboration
  • Apply foundational and advanced medical knowledge to deliver evidence-informed, patient-centered care
  • Integrate clinical insight with scientific reasoning to inform translational research and improve health outcomes
  • Lead and collaborate effectively within interdisciplinary teams, fostering inclusive, ethical, and productive research and clinical environments
  • Communicate complex scientific and clinical concepts clearly and professionally to patients, trainees, colleagues, and diverse stakeholders

Vision

To develop physician-scientists who integrate rigorous biomedical research with medical practice to advance discovery, translate science into improved health outcomes, and lead ethically within academic medicine.

Values

At the core of our program, we are guided by a commitment to the following values that drive our mission:

  • Compassion: We act with kindness, empathy, and dignity.
  • Collaboration: We achieve common goals through teamwork and partnerships.
  • Innovation: We drive transformation by embracing new ideas, discoveries, and practices.
  • Integrity: We do the right thing and commit to accountability in words, actions, and use of resources.
  • Respect: We value everyone and their many perspectives to build trust and a sense of belonging.

Mission

To train the future generation of physician-scientists and leaders in academic medicine.

Stories worth sharing

Stay connected to the discoveries, milestones, and experiences shaping the MSTP community.