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Division of Hematology & Oncology

Advance cancer and blood disorder discovery and care alongside expert clinicians and researchers shaping innovative treatments and training the next generation of leaders.

At the forefront of cancer research, MUSC Hollings Cancer Center (HCC) is one of fewer than 75 National Cancer Institute-designated cancer centers in the nation and the only one in South Carolina. This research is the driving force behind delivering medical advances to patients and their families, enabling us to educate health care professionals and the public and to establish outreach services for underserved populations across the state.

As an integral component of the Hollings Cancer Center, the MUSC Division of Hematology & Oncology builds upon a long history of excellence in hematology and hematological malignancies, as well as solid tumor oncology and bone marrow transplant. Division faculty are leaders in the fields of cancer care and blood disorders. In the latest rankings by U.S. News & World Report, MUSC Health's Hematology/Oncology program ranked as high-performing for the treatment of cancer.

US News and World Report cancer badge.

Leading Progress in Cancer and Hematologic Medicine

The division’s fellowship program continues to recruit top tier candidates and is the only hematology oncology training program in the state of South Carolina. The program provides each fellow extensive clinical training in outpatient, inpatient, and consultative medical oncology and benign and malignant hematology, including autologous and allogeneic stem cell transplantation.

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Our faculty lead pioneering research and clinical trials, expanding treatment options for cancers and blood disorders. As an NCI-Designated Cancer Center, Hollings offers exclusive therapies and trials unavailable elsewhere in South Carolina.

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As a statewide referral center, our division specializes in solid tumor oncology, malignant and benign hematology, and bone marrow transplants. With a dedicated clinical team, we provide exceptional care at Hollings Cancer Center, the Ralph H. Johnson VA Medical Center, Medical University Hospital, and Ashley River Tower.

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Latest impact in hematology and oncology

A. Craig Lockhart, M.D., MHS, FASCO

Chief, Division of Hematology & Oncology
Associate Director, Clinical Science, Hollings Cancer Center
Professor, College of Medicine
Grace DeWolff Professor of Medical Oncology
APP Fellowship Medical Director – Hematology-Oncology

Dr. Craig Lockhart is the Director of the Division of Hematology & Oncology at MUSC and Associate Director for Clinical Science at MUSC Hollings Cancer Center. His research specialty is gastrointestinal cancers, and he has been a principal investigator on more than 100 Phase I/II and III trials.

Prior to joining MUSC, Dr. Lockhart was on the faculty and in leadership roles at the University of Miami, Miller School of Medicine, Washington University in St. Louis/Siteman Cancer Center, and at Vanderbilt University/Vanderbilt-Ingram Cancer Center.

Dr. Lockhart has been conducting early-phase clinical trials for over 20 years. His specific research interests are developing and conducting Phase I/II clinical trials of novel therapeutics applied to gastrointestinal cancers. In treating these cancers, he aims to incorporate novel agents or molecular/genetic-based treatments into therapeutic trials in the pursuit of personalized cancer care. He has developed and led multi-institutional clinical trials involving the treatment of GI tumors through national cooperative groups as well as investigator-initiated studies. He has been an investigator and co-investigator on individual grants, on successful SPORE grant applications and on successful multi-institutional UM1 grant applications.

Dr. Lockhart has also served on several committees for the American Society of Clinical Oncology (ASCO), including the scientific and career development committees. He has been a member of the National Comprehensive Cancer Network (NCCN) guidelines committee for gastric and esophageal cancers. He also serves as faculty at the ASCO/American Association for Cancer Research (AACR) Methods in Clinical Cancer Research Workshop, mentoring fellows and junior faculty on the development of gastrointestinal cancer therapeutic protocols.

Dr. Lockhart graduated from the University of Texas Southwestern Medical School at Dallas in 1993. He completed residency training at Barnes Hospital at Washington University, fellowship training in hematology/oncology at Duke University and a fellowship in drug development at GlaxoSmithKline in the North Carolina Research Triangle Park. He also earned a Master of Health Science degree in clinical trials at Duke University. He completed his undergraduate degree, a bachelor’s in biology, at Rice University.

Contact Our Division

MSC 635
Walton Research Building
39 Sabin St
Charleston, SC 29425

Main: 843-792-4271

Fax: 843-792-0644

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