Skip to main content

Clinical Research Program

Advancing Discovery. Improving Patient Care.

The Pulmonary and Critical Care Clinical Research Program at MUSC is advancing the future of lung and critical care medicine through innovative clinical research. Backed by a strong research infrastructure and experienced investigators, we conduct Phase I, II, and III clinical trials that bring promising therapies to patients while advancing scientific discovery.

As a leading academic medical center, MUSC is consistently among the top-enrolling sites for multicenter clinical trials. Led by Patrick Flume, M.D., our program supports more than 100 active clinical studies with a dedicated team of 30+ research professionals working across a wide range of pulmonary and critical care conditions, including cystic fibrosis, idiopathic pulmonary fibrosis, pulmonary arterial hypertension, sarcoidosis, sepsis, and other acute and chronic lung diseases.

Research Infrastructure that Supports Innovation

Our comprehensive clinical research infrastructure enables efficient, high-quality study execution from enrollment through biospecimen management. Dedicated laboratory space, specialized equipment, and secure specimen storage support the collection, processing, storage, and shipment of biological samples. Investigators also have access to MUSC's CTSA-funded biorepository for advanced specimen processing and long-term storage.

All research personnel are trained in accordance with 49 CFR and IATA regulations, ensuring the safe, compliant handling and transport of research specimens.

Collaborate with Us

Whether you're a faculty member seeking research collaboration, a resident, fellow, or medical student exploring research opportunities, or an industry or academic partner interested in clinical trials, we welcome the opportunity to work together.

Learn more about our ongoing studies and research opportunities by contacting Ashley Warden, Clinical Research Manager, at 843-792-4349 or jonesash@musc.edu.

Our Clinical Research Investigators

Patrick A. Flume, M.D.

Associate Vice President for Clinical Research

Rahul Argula, M.D.

J. Terrill Huggins, M.D.

W. Ennis James, M.D.

Section Chief, Ambulatory
Program Director, Susan Pearlstine Sarcoidosis Center of Excellence
Professor - College of Medicine

Rachana Krishna, M.D.

Pulmonologist

Aravind Menon, M.D.

Assistant Professor, Pulmonary, Critical Care, Allergy and Sleep Medicine

Christina Mingora, M.D.

Fellow, Division of Pulmonary, Critical Care, Allergy & Sleep Medicine

Luca Paoletti, M.D.

Denise Sese, M.D.

Brandie Taylor, NP

Timothy P. M. Whelan, M.D.

ICCE Chief, Pharmacy
Professor, College of Medicine

Clinical Research Program Manager

Ashley Warden, CCRC