If your study involves cancer or cancer patients, your study will need to be approved by the Hollings cancer center protocol review committee (PRC). This process should be initiated as soon as possible to avoid any delays with the study process. Prior to being assigned to a PRC meeting for review and approval, the study must first be pre-approved by a Hollings Cancer Center disease focus group (DFG).
In accordance with the HCC Protocol Review and Monitoring System, all cancer-related hypothesis-driven clinical research studies conducted at MUSC must first be reviewed by the respective Disease Focus Group for an initial assessment of value, fit, and prioritization within the existing trial portfolio.
DFGs:
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Phase I unit
- Breast
- Gastrointestinal
- Genitourinary
- Gynecological
- Head and neck
- Hematological malignancies
- Melanoma
- Neurological
- Pediatric
- Sarcoma
- Thoracic
Studies will then be reviewed by the HCC Protocol Review Committee (PRC) for scientific merit.
This may include studies that target cancer patients or studies enrolling non-cancer patients that include cancer-related objectives (e.g., cancer control trials, cancer diagnostic trials, epidemiological and behavioral studies and health services research).
Per the MUSC Institutional Review Board (IRB), any cancer-related trials will automatically be routed to the PRC. For any institutional trial that is subject to PRC review, approval must be obtained prior to IRB review. All other studies that are not institutional trials may undergo PRC and IRB review simultaneously. HCC PRC approval must be obtained and submitted in eIRB before IRB approval is released.
Protocol Review Committee - New Form (musc.edu)