RMCB Seminar Archive

Departmental Seminar Organizer: Dr. Antonis Kourtidis


September 1, 11:00 am

  • Samar Hammad, Ph.D.
    Associate Professor, Regenerative Medicine & Cell Biology, MUSC - Works in Progress
    "Sphingolipids: The New Metabolic Predictors Independent from Traditional Markers: The Lupus Story"

September 8, 11:00 am

  • Hongkuan Fan, Ph.D.
    Associate Professor, Pathology and Laboratory Medicine, MUSC
    "The Role of Fli-1 in Pericyte Dysfunction in Alzheimer’s Disease Development"

September 15, 11:00 am

  • Roy Parker, Ph.D.
    Professor, Biochemistry, University of Colorado Boulder
    "RNP Granules in Health and Disease"

September 22, 11:00 am

  • Scott Summers, Ph.D.
    Professor, Nutrition & Integrative Physiology, University of Utah
    "Ceramides and the Two Phases of Lipotoxicity"

September 29, 11:00 am

  • Ramesh A. Shivdasani, M.D., Ph.D.
    Professor of Medicine, Dana-Farber Cancer Institute and Harvard Medical School
    "Epigenetic Exploration of Barrett’s Esophagus and Gastric Intestinal Metaplasia"

October 6, 11:00 am

  • Mindy Engevik, Ph.D.
    Assistant Professor, Regenerative Medicine & Cell Biology, MUSC - Works in Progress
    "First contact: the role of the intestinal mucus layer in microbiota-host interactions"

October 13, 11:00 am

  • Kathryn E. Hamilton, Ph.D.
    Assistant Professor, Department of Pediatrics, UPenn
    "IMP-licating RNA binding proteins in intestinal epithelial regeneration"

October 20, 11:00 am

  • Benoit Bruneau, Ph.D.
    Professor, UCSF - Director, Gladstone Institute of Cardiovascular Disease
    "Transcriptional regulation of heart development and disease"

October 27, 11:00 am

  • Mark R. Frey, Ph.D.
    Associate Professor, Biochemistry & Molecular Medicine, University of Southern California
    "Dynamic regulation of cell differentiation in the gut epithelium"

November 3, 11:00 am

  • Amy Engevik, Ph.D.
    Assistant Professor, Regenerative Medicine & Cell Biology, MUSC - Works in Progress
    "Dissecting the role of Myosin Vb in mucus and drug efflux"

November 10, 11:00 am

  • Wayne Lencer, M.D.
    Professor of Pediatrics, Harvard Medical School
    "Mucosal absorption of therapeutic peptides enabled by harnessing the endogenous sorting of glycosphingolipids"

November 17, 11:00 am

  • David Merryman, Ph.D.
    Professor of Biomedical Engineering, Vanderbilt
    "Emerging mechanobiological strategies for treating cardiopulmonary disease"

December 1, 11:00 am

  • George Daley, M.D., Ph.D.
    Professor of Medicine, Harvard Medical School
    "Blood from a Petri Dish"

December 8, 11:00 am

  • Oded Rechavi, Ph.D.
    Professor, Tel-Aviv University, Israel
    "Really Long Term Memories in C. elegans Nematodes"

December 15, 11:00 am

  • Didier Stainier, Ph.D.
    Professor, Max Planck Institute for Heart and Lung Research, Germany
    "Cardiac regeneration in zebrafish and medaka"


January 12, 11:00 am

  • Xavier Trepat, Ph.D.
    Group Leader, Institute for Bioengineering of Catalonia, Spain
    "Mechanobiology of intestinal organoids"

January 19, 11:00 am

  • Antonis Kourtidis, Ph.D.
    Regenerative Medicine & Cell Biology - Works in Progress
    "Epithelial cell mechanoregulation through an adherens junction - associated RNAi machinery"

January 26, 11:00 am

  • Andrew Marks, M.D.
    Professor and Chair, Department of Physiology and Cellular Biophysics, Columbia University
    "Structural studies of the ryanodine receptor reveal mechanisms for arrhythmias and novel therapy"

February 2, 11:00 am

  • Silvia Guglietta, Ph.D.
    Department of Microbiology and Immunology, MUSC
    "COMPLEMENTing innate immunity to achieve gut health in intestinal diseases and beyond"

February 9, 11:00 am

  • Marino Zerial, Ph.D.
    Group Leader, Max Planck Institute of Molecular Cell Biology and Genetics
    "Mechanisms of hepatocyte polarization and liver tissue morphogenesis"

February 16, 11:00 am

  • Gabriel Núñez, M.D.
    Professor, Department of Pathology, University of Michigan
    "Host-Microbiota Interactions in Health and Disease"

February 23, 11:00 am

  • Mahmood Hussain, Ph.D.
    Professor, NYU Long Island School of Medicine
    "Role of MTP and lipid metabolism"

March 2, 11:00 am

  • Silvia Vilarinho, MD, Ph.D.
    Assistant Professor of Medicine and Pathology, Yale School of Medicine
    "Genes, Genomes and Liver Disease"

March 9, 11:00 am

  • Ge Tao, Ph.D.
    Regenerative Medicine & Cell Biology - Works in Progress

March 16, 11:00 am

  • Randy Schekman, Ph.D.
    Professor, Molecular and Cell biology, University of California Berkeley

March 23, 11:00 am

  • Charles Chan, M.D.
    Assistant Professor, Department of Surgery, Stanford University School of Medicine
    "Skeletal Stem Cells and Beyond"

March 30, 11:00 am

  • Hao Zhu, M.D., Ph.D.
    Children’s Medical Center Research Institute, UT Southwestern
    "Cellular and genetic contributions to regeneration in healthy and diseased livers"

April 6, 11:00 am

  • No Seminar (DDRCC retreat)

April 13, 11:00 am

  • Henry Sucov, Ph.D.
    Regenerative Medicine & Cell Biology - Works in Progress
    "Causes and Consequences of Cardiomyocyte Polyploidy"

April 20, 11:00 am

  • Yasuko Iwakiri, Ph.D.
    Professor of Medicine, Internal Medicine/Digestive Diseases, Yale School of Medicine
    "Hepatic lymphatics in health and disease"

April 27, 11:00 am

  • No Seminar

May 4, 11:00 am

  • Jorge Munera, Ph.D.
    Regenerative Medicine & Cell Biology - Works in Progress
    "Elucidating mechanisms of human hindgut development using human pluripotent stem cell derived organoids"

May 11, 11:00 am

  • Joseph Hyser Ph.D.
    Department of Molecular Virology & Microbiology, Baylor College of Medicine
    "A HOSTile takeover of Ca2+ signaling during enteric virus infections"

May 18, 11:00 am

  • Anna Mae Diehl, M.D.
    Florence McAlister Distinguished Professor, Department of Medicine, Duke
    "Metabolic Reprogramming and Liver Repair"

May 25, 11:00 am

  • Glenn Radice, Ph.D.
    Department of Medicine, Cardiology Division, The Warren Alpert Medical School, Brown University
    "Molecular Control of Mechanical Forces during Cardiac Development and Disease"

2020-2021 Seminar Series


September 2, 11:00 am

  • Alejandro Adam, Ph.D.
    Associate Professor, Molecular and Cellular Physiology, Albany Medical Center
    "IL-6-induced vascular leakage and multiorgan dysfunction"

September 9, 11:00 am

  • James Heslop, Ph.D.
    Postdoctoral Fellow, Steve Duncan lab, Regenerative Medicine and Cell Biology - Works in Progress
    "GATA6 defines endoderm fate by controlling chromatin accessibility"

September 16, 11:00 am

  • Hans Clevers, M.D., Ph.D.
    Molecular Genetics, University Medical Center and Hubrecht Institute, Utrecht, Netherlands
    "Organoids to model human disease"

September 23, 11:00 am

  • Stephan Huveneers, Ph.D.
    Medical Biochemistry, Academic Medical Center, University of Amsterdam, Netherlands
    "Endothelial adhesions sense forces for angiogenesis"

September 30, 11:00 am

  • Mary Estes, Ph.D.
    Virology and Medicine, Infectious Disease and Gastroenterology, Baylor College of Medicine
    "Translating Stem Cell Biology to Understand Human Gastrointestinal Infections"

October 7, 11:00 am

  • Johanna Ivaska, Ph.D.
    Molecular Cell Biology, University of Turku, Finland
    "Seeing the invisible: adhesions and forces in cancer cell invasion and pluripotency"

October 14, 11:00 am

  • Bernd Schnabl, M.D.
    Gastroenterology, School of Medicine, UCSD
    "Translating microbiota research into therapies for human liver disease"

October 21, 11:00 am

  • Elda Grabocka, Ph.D.
    Cancer Biology & Surgery, Thomas Jefferson University and Kimmel Cancer Center
    "Stress granules: a stress-adaptive mechanism in KRAS-driven pancreatic tumorigenesis"

October 28, 11:00 am

  • Antonis Kourtidis, Ph.D.
    Assistant Professor, Regenerative Medicine & Cell Biology - Works in Progress
    "Novel functions of cadherin complexes"

November 4, 11:00 am

  • Carolina Eliscovich, Ph.D.
    Research Assistant Professor, Medicine and Anatomy & Structural Biology, Albert Einstein College of Medicine
    "Imaging mRNA expression to understand liver during regeneration"

November 11, 11:00 am

  • Kristy Red-Horse, Ph.D.
    Associate Professor, Biology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University
    "Coronary artery development and repair"

November 18, 11:00 am

  • Jorge Munera, Ph.D.
    Assistant Professor, Regenerative Medicine & Cell Biology - Works in Progress
    "Modeling human hindgut development using pluripotent stem cell derived organoids"

December 2, 11:00 am

  • Fiona Watt, FRS, FMedSci
    Centre for Stem Cells & Regenerative Medicine, King's College London, UK
    "Exploring Skin Cell Heterogeneity"

December 9, 11:00 am

  • Jiandie Lin, Ph.D.
    Cell & Developmental Biology, University of Michigan Medical School
    "Hormonal signaling in metabolic health and disease"

December 16, 11:00 am

  • Ge Tao, Ph.D.
    Assistant Professor, Regenerative Medicine & Cell Biology - Works in Progress
    "Programmed death of cardiomyocytes after myocardial infarction"


January 6, 11:00 am

  • Joseph Wu, M.D., Ph.D.
    Professor, Cardiovascular Medicine & Radiology, Stanford University
    "Stem Cells and Genomics for Precision Medicine"

January 13, 11:00 am

  • Elaine Fuchs, Ph.D.
    Professor, Mammalian Cell Biology and Development, Rockefeller University and Howard Hughes Medical Institute
    "Skin Stem Cells: Survival of the Fittest"

January 20

  • No Seminar (Inauguration Day)

January 27, 11:00 am

  • Henry Sucov, Ph.D.
    Professor, Regenerative Medicine and Cell Biology - Works in Progress
    "Causes and Consequences of Cardiomyocyte Polyploidy"

February 3, 11:00 am

  • Jerrold Turner, M.D., Ph.D.
    Professor, Pathology, Harvard Medical School; Medicine, Brigham And Women's Hospital
    "Epithelial Junctions and Mucosal Barriers: From Cell Biology to Therapy"

February 10, 11:00 am

  • Shuibing Chen, Ph.D.
    Associate Professor, Surgery and Biochemistry, Weill Cornell Medical College
    "Human Pluripotent Stem Cells, Disease Modeling and Drug Screening"

February 17, 11:00 am

  • Chip Norris, Ph.D.
    Professor, Regenerative Medicine and Cell Biology - Works in Progress
    "Leveraging human genetics to dissect syndromic and non-syndromic connective tissue diseases"

February 24, 11:00 am

  • Iliyan Iliev, Ph.D.
    Microbiology and Immunology in Medicine, Weill Cornell
    "Gut Mycobiota in Host Immunity and Inflammation"

March 3, 11:00 am

  • Jun Hee Lee, Ph.D.
    Associate Professor, Molecular & Integrative Physiology, University of Michigan
    "Microscopic Examination of Gastrointestinal Spatial Transcriptome using Seq-Scope"

March 10, 11:00 am

  • Steven D. Leach, M.D.
    Professor, Molecular and Systems Biology, Surgery, Medicine, Dartmouth
    "Mixed Messages: Altered mRNA Splicing in Pancreatic Cancer"

March 17, 11:00 am

  • Naohiro Yamaguchi, Ph.D.
    Assistant Professor, Regenerative Medicine and Cell Biology - Works in Progress
    "Ryanodine Receptor Ions Channels: Functional Implications of Mutations in Protein Complex and Human Cardiomyocytes"

March 24, 11:00 am

  • Konstantinos Drosatos, MSc, Ph.D., FAHA
    Pharmacology, Lewis Katz School of Medicine, Temple University
    "KLF5: An Underappreciated Regulator of Cardiomyocyte Metabolism in Cardiac Pathology"

March 31, 11:00 am

  • Robin Muise-Helmericks, Ph.D.
    Associate Professor, Regenerative Medicine and Cell Biology - Works in Progress
    "Akt3 Links Mitochondrial Function and Mitosis: Regulation of Mitotic Catastrophe"

April 7, 11:00 am

  • Danijela Matic Vignjevic, Ph.D.
    Cell Biology and Cancer, Institut Curie
    "Cell Migration in Gut Homeostasis and Cancer Invasion"

April 14, 11:00 am

  • Roeland Nusse, Ph.D.
    Professor, Cancer Research and Developmental biology, Stanford University School of Medicine
    "Food Cycles and Cell Cycles"

April 21, 11:00 am

  • Yukiko Sugi, Ph.D.
    Associate Professor, Regenerative Medicine and Cell Biology - Works in Progress
    "BMP-Notch Signaling Interaction in AV Valvulogenesis and Valve Disease Progression"

April 28, 11:00 am

  • Brent Stockwell, Ph.D.
    Professor, Biological Sciences and Chemistry, Columbia University
    "New Insights into GPX4 and Ferroptosis through Analysis of a Patient Variant"

May 5, 11:00 am

  • Janet Rossant, Ph.D., CC, FRS, FRSC
    Professor, Molecular Genetics and Obstetrics & Gynaecology, University of Toronto
    "Stem Cells, Embryos and Embryo Models"

May 12, No Seminar

May 19, 11:00 am

  • Andy Wessels, Ph.D.
    Professor, Regenerative Medicine and Cell Biology - Works in Progress
    "SOX9 and its Role in Valvuloseptal Development"

May 26, 11:00 am

  • Ling Qi, Ph.D.
    Molecular & Integrative Physiology, University of Michigan

    "Defining the Role of ER-associated Degradation in Health and Disease"

2019-2020 Seminar Schedule

September 4
Postponed due to Hurricane Dorian

   11 Alexander Alekseyenko, PhD Public Health Sciences, MUSC Microbiome Data Science and Informatics
   18 Giovanni Ferrari, PhD Surgery, Columbia University Physiology & Mechanobiology of Heart Valve Disease in Adult and Children: A Precision Medicine Approach
   25 Anand Mehta, D.Phil. Cell and Molecular Pharmacology, MUSC GlycoTest, GlycoPath, GlycoCure: Diagnosis, Prognosis, and Treatments for Hepatocellular Carcinoma
Denis Guttrige, PhD Pediatrics, MUSC NF-kB Involvement in Pancreatic Cancer
   9 Ann-Marie Broome, PhD
Cell and Molecular Pharmacology, MUSC NanoDelivery Systems for Drugs and Diagnostics – Winning BIG by Getting Small
   16 Seok-Hyung Kim, PhD
Medicine, MUSC Etfa Haploinsufficiency-Mediated Steatohepatitis and Roles of FAD in Liver Pathogenesis
   23 Kristine DeLeon-Pennell, PhD Medicine, MUSC
CD8 T-cells in post-MI Wound Healing
   30 Eduardo Maldonado, PhD Cell and Molecular Pharmacology, MUSC "Mitochondrial Ways": the Killing of Hepatocarcinoma Cells
Timothy McKinsey, PhD Medicine, Division of Cardiology, University of Colorado Epigenetic Therapies for Heart Failure
   13 Nancy DeMore, MD Surgery, MUSC
Development of a Humanized Monoclonal Antibody to Secreted Frizzled Related Protein 2 for Cancer
   20 Mythreye Karthikeyan, PhD Molecular Cellular Pathology, University of Alabama, Birmingham Matrix Remodeling, Cellular Plasticity and Metabolism: Insights from TGFbeta Signaling
 December  4 Diana Kuo, PhD
Medicine, Columbia University
C2cd4a, Pancreatic beta Cell Function, and Human Type 2 Diabetes Susceptibility
   12 Jessica Maiers, PhD Gastroenterology and Hepatology, Mayo Clinic, College of Medicine,
Regulation of Hepatic Fibrogenesis through TANGO1 and the UPR
   18 Wendy Goodman, PhD
Pathology, Case Western Reserve University
Immuno-Regulatory Roles of Estrogen in the Inflamed Intestine
Amy Engevik, PhD
Surgical Sciences, Vanderbilt University Medical Center
The Role of Myosin Vb in Maintaining Epithelial Polarity and Homeostasis
   29 Melinda Engevik, PhD
Pathology, Baylor College of Medicine
Bugs as Drugs: Using Bifodobacteria to Promote Intestinal Wound Repair
February  5 Jessica Thaxton, PhD Orthopaedics and Physical Medicine, MUSC Metabolic Requisites for T Cell Translation in Tumors
Aaron Zorn, PhD Cincinnati Children's Hospital Single Cell Transcriptomics Reveals a Signaling Roadmap Coordinating Endoderm and Mesoderm Lineage Diversification during Foregut Organogenesis
   19 Michele Battle, PhD Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin Novel Roles for GATA Factors in Gastrointestinal Tract Homeostasis and Disease
   26 Jie Fan, MD
Department of Surgery, University of Pittsburgh
Cell-Cell Interaction Mechanisms in Innate Immune Shifting and Acute Lung Inflammation
March 4
Shahid Husain, PhD
Ophthalmology, MUSC Epigenetics & Opioids: Their Roles in Retinal Ganglion Cell Neuroprotection
   11 Jen Wang, PhD
Cell and Molecular Pharmacology, MUSC
CDK6 in T- cell Acute Lymphoblastic Leukemia Progression
   18     Cancelled due to COVID-19
   25     Cancelled
April  1     Cancelled

   15     Cancelled

   29     Cancelled

   13     Cancelled