model of molecular structure

Publications

Complete List of Published Work in MyBibliography:  

  1. Múnera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han L, Campbell I, Mahe MM, McCauley HA, Zhang X, Sundaram N, Hudson JR, Zarsozo-Lacoste A, Pradhan S, Tominaga K, Sanchez JG, Weiss AA, Chatuvedi P, Spence JR, Hachimi M, North T, Daley GQ, Mayhew CN, Hu Y, Takebe T, Helmrath MA, and Wells JM. (2023) Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon. Cell Stem Cell. Nov 2;30(11). PMID: 37922878. 
  2. Han L, Wu Y, Fang K, Sweeney S, Roesner UK, Parrish M, Patel K, Walter T, Piermattei J, Trimboli A, Lefler J, Timmers CD, Yu XZ, Jin VX, Zimmermann MT, Mathison AJ, Urrutia R, Ostrowski MC & Leone G. (2023) The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis. Nat Commun 14, 1. PMC9810714. 
  3. Lefler JE, MarElia-Bennett CB, Thies KA, Hildreth BE, Sharma SM, Pitarresi JR, Han L, Everett C, Koivisto C, Cuitino MC, Timmers CD, O'Quinn E, Parrish M, Romeo MJ, Linke AJ, Hobbs GA, Leone G, Guttridge DC, Zimmers TA, Lesinski GB, Ostrowski MC. (2022) STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer. Life Sci Alliance. Nov;5(11). PMC9270499.  
  4. Kishimoto K, Iwasawa K, Sorel A, Ferran-Heredia C, Han L, Morimoto M, Wells JM, Takebe T, Zorn AM. (2022) Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems. Nat Protoc. Aug 17;. doi: 10.1038/s41596-022-00733-3. Review. PMID: 35978039. 
  5. Han L, Seward C, Leone G, Ostrowski M. (2022) Origin, activation and heterogeneity of fibroblasts associated with pancreas and breast cancers. Adv Cancer Res. Mar 154:169-201. PMID: 35459469. 
  6. Eicher A, Kechele D, Sundaram N, Berns H, Poling H, Haines L, Sanchez JG, Kishimoto K, Krishnamurthy M, Han L, Zorn A, Helmrath M, Wells J. (2022) Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell Stem Cell. Jan 6;29(1):36-51.e6. PMC8741755. 
  7. Han L*, Chaturvedi P*, Kishimoto K*, Koike H*, Nasr T, Iwasawa K, Giesbrecht  K, Witcher PC, Eicher A, Haines L, Lee Y, Shannon JM, Morimoto M, Wells J, Takebe T, Zorn A. (2020) Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis. Nat Commun. 27;11(1):4158. PMC7453027. *co-first author 
  8. Nasr T, Mancini P, Kinney J, Daniels K, Vardanyan J, Edwards N, Agricola Z, Han L, Trisno A, Kofron M, Cha S, Rankin S, Kenny A, Wells J, Zorn A. (2019) Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation. Dev Cell. 16;51(6):665-674.e6. PMID: 31813796. 
  9. Trisno S, Philo K, McCracken K, Catá E, Ruiz-Torres S, Rankin S, Han L, Nasr T, Chaturvedi P, Rothenberg M, Mandegar M, Wells S, Zorn A, Wells J. (2018) Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification. Cell Stem Cell. 4;23(4):501-515.e7. PMC6225525.  
  10. Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV. (2018) FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 1;443(1):50-63. PMC6191344. 
  11. Rankin S, McCracken K, Luedeke D, Han L, Wells J, Shannon S and Zorn A. (2018) Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis. Dev Biol. 1;434(1):121-132. PMC5785443. 
  12. Han L, Xu J, Grigg E, Slack M, Chaturvedi P, Jiang R, Zorn AM. (2017) Osr1 Functions Downstream of Hedgehog Pathway to Regulate Foregut Development. Dev Biol. 427(1):72-83. PMC5519324 
  13. Han L*, Nasr T*, Zorn A. (2017) Mesodermal lineages in the developing respiratory system. Trends Dev Biol. Volume 9, pages 91-110. Review. *co-first author 
  14. Rankin SA*, Han L*, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM. (2016) A Retinoic Acid-hedgehog Cascade Coordinates Mesoderm-inducing Signals and Endoderm Competence during Lung Specification. Cell Rep. 16(1):66-78. PMC5314425. * co-first author.  
  15. Rankin SA, Tran HT, Wlizla M, Mancini P, Shifley ET, Bloor SD, Han L, Vleminckx K, Wert SE, and Zorn AM. (2015) A molecular atlas of xenopus respiratory system development. Dev Dyn. Jan;244(1):69-85. PMC4276498.