Mouse Behavioral Phenotyping Core (MBPC)

The MBPC’s overall goal is to provide state-of-the-art mouse behavior assessments and lower the barrier to entry for investigators integrating behavior in their research programs. Mouse phenotyping is a critical translational research approach for evaluating behaviors that are reminiscent of NDD symptoms, e.g., social deficits, communication deficits, learning and memory deficits, and hyperactivity. By providing access to sophisticated and automated testing equipment, expert training and data interpretation capabilities, and experienced technical assistance to help carry out experiments, the MBPC will enable and enhance scientific discovery in animal models of NDDs. The MBPC will ensure the success and in vivo relevance of the current and future RPL projects and will position the RPLs to be more competitive for future independent funding opportunities. MBPC leaders work with all CNDD investigators to develop preliminary data and/or experimental descriptions during preparation of NIH R01s, manuscripts, etc. Dr. Penrod-Martin directs the MBPC, and she has >15 years of experience with rodent behavior testing and data analysis, and she will be assisted by Dr. Albayram, who also has ~15 years of mouse behavior testing experience. The MBPC is also available to the general MUSC research community as a fee-for-service option to allow for studies of genetically modified mice, effects of candidate therapeutics on general behavior, and other research goals. Visit the MUSC Mouse Behavioral Phenotyping Core page for more information.