We support internal and multisite PCORnet research studies at MUSC through our involvement in the STAR Clinical Research Network.

PCORnet and the STAR Clinical Research Network seek to support multisite, EHR-data driven research by reducing technical and regulatory barriers. BMIC assists MUSC researchers in navigating these networks.

PCORnet and STAR can help researchers:

  • Assess feasibility by providing prep to research counts of patients meeting certain criteria
  • Find collaborators at other sites
  • Identify potential participants for a multi-site study (e.g., EHR data, survey, observational, or pragmatic clinical trial research)
  • Receive harmonized datasets for secondary data analyses
  • Navigate the inter-institutional contracting and regulatory processes

For more detailed information about these networks, please request a consultation to meet with the MUSC STAR CRN Project Manager.  The project manager will help you determine the best network for your project, assist with refining your request, and provide an overview of available data.




PCORnet, the National Patient-Centered Clinical Research Network, is a large, highly representative, "network of networks" that enables access to data routinely gathered in a variety of healthcare settings. PCORnet includes about 70 million patients with an encounter in the past 5 years and 32 million patients with an encounter in the previous year.


The Stakeholders, Technology, and Research Clinical Research Network (STAR CRN) is one of the 11 clinical research networks that comprise PCORnet. The STAR CRN includes: Vanderbilt Health System (lead site); UNC-Chapel Hill; Duke University; Health Sciences South Carolina (includes Medical University of South Carolina); Mayo Clinic; Meharry Medical College; Vanderbilt Healthcare Affiliated Network; and Wake Forest Baptist Health. STAR is particularly well suited for MUSC investigators who are interested in local, regional, or national collaborations. Collectively STAR includes 11 million patients with an encounter in the past 5 years and 5 million patients with an encounter in the previous year.

Additional information can be found in the PCORnet at MUSC Welcome Guide

MUSC PCORnet Research Spotlight


ACTIV-6: COVID-19 Outpatient Randomized Trial to Evaluate Efficacy of Repurposed Medications

Recruitment Contact:



Leslie Lenert, MD, MS

Associate Principal 

Site Principal Investigator


Jihad Obeid, MD


Site Co-Investigator

Team Contact