The Leadership Administrative Core (LAC) is the backbone of the MUSC SCORE operations. As it has in previous funding periods, the LAC continues to provide the organizational framework for addressing emergent issues, budgetary concerns and daily operations within the SCORE. It also ensures the integration of the SCORE within MUSC, with local and statewide officials and community treatment centers, and across the national consortium of SCOREs. The LAC provides fiscal and administrative management for all program components and scientific and programmatic leadership, manages the SCORE Pilot Project Program, supports campus-wide, regional, and national cross-SCORE collaborations, and oversees the SCORE Evaluation Program. The LAC continues to build on its previous successes to expand the MUSC SCORE’s functionality as a valuable regional and national resource on sex and gender differences in addictive disorders through the establishment of groups like the Women’s Health Research Consortium, the expansion of MUSC’s Women’s Health Research Day, and strategic partnerships with statewide treatment providers. The LAC is under the leadership of Dr. Aimee McRae-Clark.