ADRC Pilot Project Program 2021

Alzheimer’s Disease Research Center - Pilot Project Program

MUSC is developing an Alzheimer’s Disease Research Center (ADRC) to support investigators who are interested in pursuing basic, clinical or translational research of Alzheimer’s Disease and Alzheimer’s Disease Related Dementias (e.g., frontotemporal lobar dementias). The long-term goal of the Center is to offer support for such research through establishing core resources, outreach programs, and pilot studies as well as to obtain federal funding for the center.

In this RFA we invite applications through a letter of intent to support exploratory projects that are likely to lead to future funding through the National Institutes of Health, preferably the NIA, or similar. We expect to be able to support 3 projects with a max budget of $35,000 per project. The focus of the projects can be in basic or clinical biomedical, translational, and epidemiological, caregiving, educational or behavioral research.

MUSC Principal Investigators will be considered in three categories listed in order of favorability. Preference will be given to early-stage investigators as well as highly innovative and collaborative projects between investigators with different areas of expertise.

Category A: Early-stage investigators (completed terminal degree or residency) within the last 10-years who have not received independent NIH funding, with the exception of career development awards and fellowships.

Category B: Established investigators who have previously or are currently funded through the NIH or similar mechanism and who have no previous history of Alzheimer’s Disease research but would like to enter the field.

Category C: Established investigators who currently work on Alzheimer’s Disease research but who are proposing a project that departs substantially from their current program. Justification of the new direction is essential.


1. Applicants should submit an updated NIH Biosketch and a one-page letter of intent in the style of an NIH SF424 (R&R) specific aims page. For details see Additionally, applicants must include a list of proposed collaborators along with their ranks, departmental affiliations, and roles on the project. The deadline for submission of the LOI is April 30th, 2021. LOI’s should be provided as a single PDF by email to Peyton Callahan,

2. After review of the LOI, successful applicants will be asked to submit a full application, due June 7th. Specific details regarding the application process will be provided to successful applicants. However, applicants should plan on using NIH SF424 forms with a research plan that does not exceed 3 pages.

Questions regarding this RFA can be directed to Peyton Callahan,