Peggi M. Angel, Ph.D.

Assistant Professor
Department: Cell and Molecular Pharmacology and Experimental Therapeutics
Programs: Inflammation, Fibrosis

 

 

Research Interests:

Dr. Angel received her PhD from the University of Georgia, and joined the MUSC faculty in 2012 following postdoctoral work studying fetal alcohol and liver disease at Emory University and heart valve development and disease at Vanderbilt University Medical Center.

Dr. Angel’s current research focuses on defining the differences in patterns of extracellular matrix proteins and their modifications in liver inflammation, fibrosis, cirrhosis and hepatocellular carcinoma. Current projects are geared toward discerning differences in the post-translational modification of collagen subtypes in hepatocellular carcinoma and determining whether such differences correlate with variability in clinical outcomes. These studies use tissue imaging proteomics – a unique strength of the MUSC Proteomics and Mass Spectrometry Core – to help understand the histological localization of collagen signatures within a tissue section. The Angel lab also works to develop new high throughput imaging mass spectrometry technologies that help investigators rapidly profile metabolic biomarkers present in patient derived serum, cells and tissues.

Publications:

PubMed Collection