Cardiology

Amy Bradshaw, Ph.D.

bradshad@musc.edu

Our lab studies extracellular matrix in myocardial growth and remodeling.

Kristine Y. DeLeon-Pennell, Ph.D.

deleonky@musc.edu

The DeLeon-Pennell Lab focuses on the inflammatory and fibrotic components of cardiac remodeling following a heart attack (myocardial infarction; MI). This includes evaluating how existing variables such as gender or aging changes these processes. Our major research focus is on the role of the adaptive immune system and the interplay with the innate immune system to regulate cardiac wound healing. These changes include cell-cell and cell-matrix interactions, which both affect and react to processes involved in tissue repair.

Valerian Fernandes, M.D.

Contact Linda Walton: waltonlv@musc.edu

Ongoing research projects

  1. Alcohol septal ablation for hOCM- multiple students doing flex have worked on subprojects
  2. STEMI analysis at MUSC- before and after COVID
  3. Rotational atherectomy for complex coronaries- RHJ VAMC
  4. Left Main interventions outcomes at RHJ VAMC

The student will work on the Alcohol Septal Ablation database and Rotational Atherectomy database; complete data entry in conjunction with residents and fellows on the research team; work on specific sub-project with an aim to submit an abstract to a national meeting and help with manuscript writing; submit their work as an abstract at the MUSC Research Day; do sessions on Research Methodology and data analysis; attend all weekly research meetings and present their work.

Award winning abstracts by CRI interns Ralph H. Johnson VAMC Student Research 1st Place Winner "Long-Term Outcomes of Hypertrophic Cardiomyopathy Patients Following Alcohol Septal Ablation Exhibit No Improvement in BMI Despite Improved Heart Function And Returning to General Population Mortality"

Ralph H. Johnson VAMC Student Research Young Investigator Award "Out with the Old and In with the Great: Alcohol Septal Ablation Outcomes on Race, Gender and Age"

Samples of published research by former CRI interns Leaphart et al. 2019 and Cai et al., 2018.