The lateral habenula is not required for ethanol dependence-induced escalation of drinking.

Nentwig TB, Vaughan DT, Braunscheidel KM, Browning BD, Woodward JJ, Chandler LJ. Neuropsychopharmacology. 2022 Jun 18. doi: 10.1038/s41386-022-01357-7. Epub ahead of print. PMID: 35717465.

Behavioral and slice electrophysiological assessment of DREADD ligand, deschloroclozapine (DCZ) in rats.

Nentwig TB, Obray JD, Vaughan DT, Chandler LJ. Sci Rep. 2022 Apr 21;12(1):6595. doi: 10.1038/s41598-022-10668-0. PMID: 35449195; PMCID: PMC9023443.

Adolescent Alcohol Exposure Results in Sex-specific Alterations in Conditioned Fear Learning and Memory in Adulthood.

Chandler LJ, Vaughan DT, Gass JT. Front Pharmacol. 2022 Feb 8;13:837657. doi: 10.3389/fphar.2022.837657. PMID: 35211024; PMCID: PMC8861326.

The role of sex in the persistent effects of adolescent alcohol exposure on behavior and neurobiology in rodents.

Robinson DL, Amodeo LR, Chandler LJ, Crews FT, Ehlers CL, Gómez-A A, Healey KL, Kuhn CM, Macht VA, Marshall SA, Swartzwelder HS, Varlinskaya EI, Werner DF. Int Rev Neurobiol. 2021;160:305-340. doi: 10.1016/bs.irn.2021.07.007. Epub 2021 Aug 11. PMID: 34696877; PMCID: PMC8672816.

Impact of sex, strain, and age on blood ethanol concentration and behavioral signs of intoxication during ethanol vapor exposure.

Glover EJ, Khan F, Clayton-Stiglbauer K, Chandler LJ. Neuropharmacology. 2021 Feb 15;184:108393. doi: 10.1016/j.neuropharm.2020.108393. Epub 2020 Nov 19. PMID: 33221480; PMCID: PMC7855756.

Chronic intermittent ethanol and lipopolysaccharide exposure differentially alter Iba1-derived microglia morphology in the prelimbic cortex and nucleus accumbens core of male Long-Evans rats.

Siemsen BM, Landin JD, McFaddin JA, Hooker KN, Chandler LJ, Scofield MD. J Neurosci Res. 2021 Aug;99(8):1922-1939. doi: 10.1002/jnr.24683. Epub 2020 Jul 3. PMID: 32621337; PMCID: PMC7779701.

Selective Deficits in Contingency-Driven Ethanol Seeking Following Chronic Ethanol Exposure in Male Mice.

Barker JM, Bryant KG, Montiel-Ramos A, Goldwasser B, Chandler LJ. Alcohol Clin Exp Res. 2020 Sep;44(9):1896-1905. doi: 10.1111/acer.14418. Epub 2020 Aug 20. PMID: 32735737; PMCID: PMC8686207.

Effects of Ethanol on Plasma Ghrelin levels in the Rat During Early and Late Adolescence.

Healey KL, Landin JD, Dubester K, Kibble S, Marquardt K, Brutman JN, Davis JF, Swartzwelder HS, Chandler LJ. Alcohol. 2020 Jan 7. pii: S0741-8329(19)30042-4. doi: 10.1016/j.alcohol.2019.12.006. [Epub ahead of print]

Mechanisms of Persistent Neurobiological Changes Following Adolescent Alcohol Exposure: NADIA Consortium Findings.

Crews FT, Robinson DL, Chandler LJ, Ehlers CL, Mulholland PJ, Pandey SC, Rodd ZA, Spear LP, Swartzwelder HS, Vetreno RP. Alcohol Clin Exp Res. 2019 Sep;43(9):1806-1822. doi: 10.1111/acer.14154. Epub 2019 Aug 14.

Inhibition of the rostromedial tegmental nucleus reverse alcohol withdrawal-induced anxiety-like behavior.

Glover EJ, Starr EM, Chao Y, Jhou TC, Chandler LJ. Neuropsychopharmacology. 2019 Oct;44(11):1896-1905. doi: 10.1038/s41386-019-0406-8. Epub 2019 May 6.

Absence of compulsive drinking phenotype in adult male rats exposed to ethanol in a binge-like pattern during adolescence

Nentwig TB, Starr EM, Chandler LJ, Glover EJ. Alcohol. 2019 Sep;79:93-103. doi: 10.1016/j.alcohol.2019.01.006. Epub 2019 Jan 18.

Inactivation of ventral hippocampus projections promotes sensitivity to changes in contingency.

Barker JM, Bryant KG, Chandler LJ. Learn Mem. 2018 Dec 17;26(1):1-8. doi: 10.1101/lm.048025.118. Print 2019 Jan.

Habitual Behavior is Mediated by a Shift in Response-Outcome Encoding in Infralimbic Cortex.

Barker JM, Glen WB, Linsenbardt DN, Lapish CC, Chandler LJ. eNeuro. 2018 Jan 3;4(6). pii: ENEURO.0337-17.2017. doi: 10.1523/ENEURO.0337-17.2017. eCollection 2017 Nov-Dec.

Age and Sex Interact to Mediate the Effects of Intermittent, High-Dose Ethanol Exposure on Behavioral Flexibility.

Barker JM, Bryant KG, Osborne JI, Chandler LJ. Front Pharmacol. 2017 Jul 7;8:450. doi: 10.3389/fphar.2017.00450. eCollection 2017.

Deficits in the extinction of ethanol-seeking behavior following chronic intermittent ethanol exposure are attenuated with positive allosteric modulation of mGlu5.

Gass JT, McGonigal JT, Chandler LJ. Neuropharmacology. 2017 Feb;113(Pt A):198-205. doi: 10.1016/j.neuropharm.2016.10.005. Epub 2016 Oct 8.

Binge-Like Alcohol Exposure During Adolescence Disrupts Dopaminergic Neurotransmission in the Adult Prelimbic Cortex.

Trantham-Davidson H, Centanni SW, Garr SC, New NN, Mulholland PJ, Gass JT, Glover EJ, Floresco SB, Crews FT, Krishnan HR, Pandey SC, Chandler LJ. Neuropsychopharmacology. 2017 Apr;42(5):1024-1036. doi: 10.1038/npp.2016.190. Epub 2016 Sep 13.

Role for the Rostromedial Tegmental Nucleus in Signaling the Aversive Properties of Alcohol.

Glover EJ, McDougle MJ, Siegel GS, Jhou TC, Chandler LJ. Alcohol Clin Exp Res. 2016 Aug;40(8):1651-61. doi: 10.1111/acer.13140. Epub 2016 Jul 8.

Signals from the Fourth Dimension Regulate Drug Relapse.

Mulholland PJ, Chandler LJ, Kalivas PW. Trends Neurosci. 2016 Jul;39(7):472-485. doi: 10.1016/j.tins.2016.04.007. Epub 2016 May 10. Review.

FMRP Mediates Chronic Ethanol-Induced Changes in NMDA, Kv4.2, and KChIP3 Expression in the Hippocampus.

Spencer KB, Mulholland PJ, Chandler LJ. Alcohol Clin Exp Res. 2016 Jun;40(6):1251-61. doi: 10.1111/acer.13060. Epub 2016 May 5. Erratum in: Alcohol Clin Exp Res. 2016 Sep;40(9):2021.

Loss of δ-GABAA receptor-mediated tonic currents in the adult prelimbic cortex following adolescent alcohol exposure.

Centanni SW, Burnett EJ, Trantham-Davidson H, Chandler LJ. Addict Biol. 2017 May;22(3):616-628. doi: 10.1111/adb.12353. Epub 2016 Jan 24.

Alcohol-induced alterations in dopamine modulation of prefrontal activity.

Trantham-Davidson H, Chandler LJ. Alcohol. 2015 Dec;49(8):773-9. doi: 10.1016/j.alcohol.2015.09.001. Epub 2015 Oct 23. Review.

Reversal of alcohol dependence-induced deficits in cue-guided behavior via mGluR2/3 signaling in mice.

Barker JM, Lench DH, Chandler LJ. Psychopharmacology (Berl). 2016 Jan;233(2):235-42. doi: 10.1007/s00213-015-4101-0. Epub 2015 Oct 8.

Glutamatergic plasticity and alcohol dependence-induced alterations in reward, affect and cognition.

Burnett EJ, Chandler LJ, Trantham-Davidson H. Prog Neuropsychopharmacol Biol Psychiatry. 2016 Feb 4;65:309-20. doi: 10.1016/j.pnpbp.2015.08.012. Epub 2015 Sep 1. Review.

Corticostriatal circuitry and habitual ethanol seeking.

Barker JM, Corbit LH, Robinson DL, Gremel CM, Gonzales RA, Chandler LJ. Alcohol. 2015 Dec;49(8):817-24. doi: 10.1016/j.alcohol.2015.03.003. Epub 2015 May 14. Review.