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model of molecular structure

Faculty Research

 

Bastia, Deepak, Ph.D.
Professor
Gaylord and Dorothy Donnelley Chair in Biomedical Sciences
Analyses of (1) the mechanisms of initiation of DNA replication of prokaryotic plasmids and (2) the termination of DNA replication of plasmid, bacterial and yeast chromosomal, and human mitochondrial DNA.

Davies, Christopher, Ph.D.
Professor
Structural basis for antibiotic resistance in pathogenic bacteria and development of new antimicrobials.

Delaney, Joe, Ph.D.
Assistant Professor
Biogenesis and pathology of copy-number alterations in cancer, particularly serous ovarian cancer.

DuBois, Raymond, M.D., Ph.D.
Professor and Dean of Medicine
The molecular, genetic, and cellular basis for colorectal cancer.

Gan, Wenjian, Ph.D.
Assistant Professor
Post-translational modifications in cell signaling pathways and cancer.

Gangaraju, Vamsi, Ph.D.
Assistant Professor Epigenetic regulation by Piwi-piRNA pathway; biogenesis and biological functions of piRNAs; environmental epigenetics; drosophila models of human diseases.

Howe, Philip H., Ph.D.
Professor and Chairman
Hans and Helen Koebig Chair in Clinical Oncology
Signaling pathways activated by transforming growth factor β1 (TGFβ1) and Wnt and their potential cross-talk in cellular models of differentiation and cancer.

Hsu, Yi-Te, Ph.D.
Associate Professor
Molecular mechanisms of apoptosis Bcl-2, Bcl-XL.

Lemasters, John, MD, Ph.D.
Professor
Cellular and molecular mechanisms of apoptosis and necrosis; organ preservation for transplantation surgery; mitochondrial physiology and pathophysiology, including mitochondrial permeability transition, mitophagy and calcium homeostasis; oxidative stress; ischemia/reperfusion; confocal and multiphoton microscopy of living cells.

Long, David T., Ph.D.
Assistant Professor
Graduate Program Director The mechanistic role of BRCA1 in DNA repair and cancer predisposition.

Olsen, Shaun, Ph.D.
Assistant Professor
Structural basis by which ubiquitin is specifically conjugated to target proteins and for how ubiquitination acts as a molecular switch that regulates growth factor signaling pathways.

Ogretmen, Besim, Ph.D.
Professor and Eminent Scholar
Roles of sphingolipid metabolism in cancer pathogenesis, chemotherapy-induced cell death, and drug resistance.

Ostrowski, Michael C., Ph.D.
Professor
WH Folk Chair in Experimental Oncology
Interactions between signaling pathways in cancer cell progression and normal cellular differentiation.

Palanisamy, Visu (Viswanathan), Ph.D.
Associate Professor
Post-transcriptional gene regulation in head and neck cancer: Role of RNA-binding proteins, miRNAs and lncRNAs.

Traktman, Paula Ph.D.
Hirschmann Endowed Professor
Dean, College of Graduate Studies
Vaccinia virus genome replication and virion morphogenesis. The role(s) of the cellular VRK1 protein kinase and BANF1 protein in normal cell function and cancer.

Yoon, Je-Hyun, Ph.D.
Assistant Professor
Regulatory noncoding RNAs in aging and cancer.

Research Faculty

Bai, Aiping, Ph.D.
Research Assistant Professor
Medicinal chemistry; computer-aided molecular design; enzyme inhibitors R&D; bioactive sphingolipids synthesis.

Cen, Bo, Ph.D.
Research Assistant Professor

Ghatak, Sibnath, Ph.D.
Research Assistant Professor

Howley, Breege, Ph.D.
Research Assistant Professor

Koivisto, Christopher, Ph.D.
Research Assistant Professor

Misra, Suniti, Ph.D.
Research Assistant Professor

Mohanty, Bidyut K., Ph.D.
Research Assistant Professor
Genome integrity; DNA replication arrest-dependent homologous recombination.

Oleinik, Natalia, Ph.D.
Research Assistant Professor

Pytel, Dariusz Ph.D.
Research Assistant Professor
The role of the PKR-like ER kinase (PERK) in the regulation of tumor growth and proliferation

Roth, Braden, Ph.D.
Research Assistant Professor

Szulc, Zdzislaw, Ph.D.
Research Associate Professor
Chemical etiology of sphingolipids structure and functions.

Wang, Dingzhi, Ph.D.
Research Professor

Wei, Jie, Ph.D.
Research Associate Professor

Emeritus Faculty

Büllesbach, Erika, Ph.D.
Associate Professor Emeritus
Hormones of insulin-like structure; chemical syntheses and structure-function relations.

Chao, Julie, Ph.D.
Professor Emeritus
Serine proteinase structure-function relationship; purification, molecular cloning, expression, and function of proteinases and proteinase inhibitors; serpin regulation of gene expression

Chao, Lee, Ph.D.
Professor Emeritus
Nucleic acid biochemistry; regulatory mechanism in gene expression; gene therapy in cardiovascular diseases.

Fernandes, Daniel, Ph.D.
Professor Emeritus
Molecular mechanisms of drug-induced gene amplification. Interactions of anticancer drugs with nuclear matrix proteins, especially DNA topoisomerase II.

Schwabe, Christian, Ph.D., D.D.S.
Professor Emeritus
Protein chemistry; biochemical evolution; chemical endocrinology.