This course is intended mainly for MS and PhD students interested in the statistical methods and issues arising in a variety of clinical trials. The course will include topics in adaptive/flexible study design, adaptive randomization, sample size estimation, missing data handling, interim analysis methods, and issues in data analysis. The course will also cover topics related to the statistician's role in clinical trials, including the presentation of statistical information and statistical monitoring of safety data. At the completion of the course, students will have the tools to collaborate with clinicians in the design and implementation of clinical trials as well as analysis of study data, and will have developed their skills in being more critical readers of the medical literature.
BMTRY 700, 724