BMTRY 781 Methods in Clinical Cancer Research


Didactic lectures will cover: (1) clinical and statistical design of phase I, II, and III trials; (2) incorporation of correlative endpoints and biomarkers in clinical trials, (3) considerations in chemotherapy, surgery, radation, and multimodality trials, (4) quality of life and other patient reported outcomes in cancer research, (5) the protocol review and IRB process, (6) informed consent, (7) data collection, trial monitoring and investigator responsibilities, (8) the grants process and mentoring.  In addition to didactic portions of the training, each trainee will have a clinical research proposal which will be developed into a "letter of intent" (LOI) for a clinical trial.  Other contact hours will take the form of a journal club where clinical research papers from journals such as Clinical Cancer Research or Journal of Clinical Oncology are discussed, and protocols that are being undertaken at HCC are reviewed and discussed.  Students will be required to attend and take part in the HCC Protocol Review Committee's monthly meetings.  


Eligible students must satisfy at least one of the following criteria: 1) The student is enrolled in the MSCR program, 2) The student is a Paul Calabresi K-12 training grant scholar, 3) The student is enrolled in a masters or PhD program in the DPHS, 4) The student has received consent of the instructor.