At MUSC, the Center for Cellular Therapy (CCT) is an FDA registered cGMP level facility that meets the most rigorous standards in the aspect of processing of cells.
Our capabilities range from immunomonitoring of patient samples to manufacturing of cellular products for immunotherapy.
The Foundation for the Accreditation of Cellular Therapy (FACT) recognizes MUSC as a Cellular Center that exceeds standards in patient care and laboratory practices.
The Center for Cellular Therapy is located on the 2nd floor of the Clinical Sciences Building. The 1000 square foot state-of-the-art facility consists of three ISO14644-1 compliant cGMP clean room suites that are fully functional and independent allowing maximal usage.
- Class 5 biosafety cabinets
- Stackable CO2 incubators
- Floor and tabletop centrifuges
- Regulating water baths
- COBE 2991 processors
- CliniMACS® cell sorter
- WAVE bioreactor
- Inverted fluorescent microscope
- Islet isolaton box and shaker
- Accuri C6 flow cytometer
- Vapor phase liquid nitrogen storage
- In house autoclave
CCT Support Activities
- Quality and Compliance
- Standard Operating Procedure Development
- Operations, Quality and Materials Management
- Clinical Trial Budget Preparation
- IND Preparation
- Equipment Management
- Document Control
- Process Development
CCT Resources at a Glance
- Reporting to regulatory agencies, sponsors, and IRB's of record
- Preparation of standard-of-care cell products for cell therapy
- Cell products for experimental IND-based cell therapy
- Full-spectrum service from minimally manipulated to extensively cultured cells
- Responsive team that develops competency in all cell manipulations, including purification, culture and cytokine expansion, antigen exposure, cell differentiation protocols, and gene transfer
- Comprehensive support--starting with IND preparation and regulatory guidance to development of Standard Operating Procedures and product delivery reimbursed by users
- Quality management, including quality assurance, quality control, and quality oversight committee